abstract：BACKGROUND:Among patients with advanced multivessel coronary disease, left ventricular (LV) function is widely variable, and clinical and angiographic correlates of ventricular dysfunction remain to be defined. METHODS:Among 73 339 patients undergoing diagnostic cardiac catheterization at a single center in China, pat...

journal_title：Chinese medical journal

authors： Gao Z,Xu B,Yang YJ,Kandzari DE,Yuan JQ,Chen J,Chen JL,Qiao SB,Wu YJ,Yan HB,Qin XW,Yao M,Liu HB,Dai J,Chen T,Teng SY,Gao RL

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Chronic obstructive pulmonary disease (COPD) is a progressive disease associated with a cellular inflammatory response mostly concerned with cigarette smoking. Chemokine receptors CCR1/5 play an important role in the inflammatory cells recruitment in the lung of COPD patients. The aim of this study was to de...

journal_title：Chinese medical journal

authors： Wang F,He B

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:The primary reasons for local recurrence and therapeutic failure in the treatment of malignant gliomas are the invasion and interactions of tumor cells with surrounding normal brain cells. However, these tumor cells are hard to be visualized directly in histopathological preparations, or in experimental glio...

journal_title：Chinese medical journal

authors： Dong J,Dai XL,Lu ZH,Fei XF,Chen H,Zhang QB,Zhao YD,Wang ZM,Wang AD,Lan Q,Huang Q

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:During cardiac arrest, the gastrointestinal tract is sensitive to ischemia. Protection of the gastrointestinal tract is a critical factor in determining prognosis following cardiopulmonary resuscitation (CPR). This study seeks to determine the extent of gastrointestinal tract injury and the potential protect...

journal_title：Chinese medical journal

authors： Lu Y,Wang S,Li CS

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:The research of cancer in patients on hemodialysis (HD) in China has not been reported. The aim of this study was to investigate the clinical and histological features and outcomes of cancer in Chinese HD patients. METHODS:The study subjects were 49 cancer patients (1.4%) out of 3448 end stage renal disease...

journal_title：Chinese medical journal

authors： Zhou L,Cao YL,Li WG,Fu FT,Zhang L,Wang X,Shi XH

更新日期：2012-12-01 00:00:00

abstract：:Twin pregnancy with mosaic partial hydatidiform mole (PHM) and survival of two healthy fetuses following in vitro fertilization and embryos transfer (IVF-ET) is a rare situation and is considered a challenge for management. A 32-year-old Chinese woman conceived twin pregnancy following IVF-ET. At 22 weeks' gestation, ...

journal_title：Chinese medical journal

authors： Sun CJ,Zhao YP,Yu S,Fan L,Wu QQ,Li GH,Zhang WY

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Cervical arthroplasty is indicated to preserve cervical motion and prevent accelerated adjacent segment degeneration. Whether accelerated adjacent segment degeneration is prevented in the long term is unclear. This trial compared adjacent segment degeneration in Bryan disc arthroplasty with that in anterior ...

journal_title：Chinese medical journal

authors： Sun Y,Zhao YB,Pan SF,Zhou FF,Chen ZQ,Liu ZJ

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:The mechanisms of endometriosis with infertility have not been fully studied. The present study aimed to assess the follicular fluid (FF) levels of prostaglandin E2 (PGE2), which plays a critical role within the ovary, and to investigate the effect of PGE2 on steroidogenesis in granulosa-lutein cells (GLCs) ...

journal_title：Chinese medical journal

authors： Wang J,Shen XX,Huang XH,Zhao ZM

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:One of the reasons for poor neuroregeneration after central nervous system injury is the presence of inhibitory factors such as Nogo. Here, we tested the inhibition of Nogo by RNA interference both in vitro and in vivo, using recombinant adenovirus-mediated transfection of short hairpin RNAs, to explore a ne...

journal_title：Chinese medical journal

authors： Sun HH,Gao F,Liu B,Yu HT,Kong N,Liu GM

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:There are definite gender differences in patients with macular holes. Menopausal women over 50 years are most affected. We aimed to observe the effect of estrogen on collagen gel contraction by cultured human retinal glial cells. It is speculated that estrogen could strengthen the tensile stress of the macul...

journal_title：Chinese medical journal

authors： Qiu QH,Chen ZY,Yin LL,Zheng Z,Wu XW

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Laparoendoscopic single-site surgery radical prostatectomy (LESS-RP) is a challenging urological procedure and needs to be further evaluated. This study was undertaken to illustrate the safety and initial results of pure LESS-RP with conventional available instruments. METHODS:A prospective clinical databas...

journal_title：Chinese medical journal

authors： Zhu G,Zhang YQ,Grange P,Walsh K,Jin B,Zhang YG,Chen X,Wang X,Wei D,Wan B,Wang JY

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:There have been no mortality/morbidity endpoint studies with losartan in Chinese heart failure patients. The objective was to evaluate the effects of high-dose vs. low-dose losartan on clinical outcomes in Chinese subjects with heart failure. METHODS:This study was a post hoc analysis of the Heart failure E...

journal_title：Chinese medical journal

authors： Hu DY,Huang J,Cai NS,Zhu WL,Li YS,Massaad R,Hanson ME,Dickstein K

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Clinical practice guidelines (CPGs) play an important role in healthcare in China as well as in the world. However, the current status and trends of Chinese CPGs are unknown. The aim of this study was to systematically review the present situation and the quality of Chinese CPGs published in the peer-reviewe...

journal_title：Chinese medical journal

authors： Chen YL,Yao L,Xiao XJ,Wang Q,Wang ZH,Liang FX,Liang H,Wang X,Shen XP,Xie CC,Yang KH

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:In many studies, obstructive sleep apnea (OSA) has been shown to be an independent risk factor for cardiovascular disease. Conversely, there are few reports establishing possible relation between OSA and venous thromboembolism (VTE). In this study, the aim is to evaluate OSA via polysomnography in patients w...

journal_title：Chinese medical journal

authors： Kezban OS,Ali NA,Umran T,Talha D,Ege GB,Peri A,Leyla YA,Hasan S

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Anisodamine is widely used in therapy for treating acute glomerulonephritis and diabetic nephropathy because it can improve renal microcirculation. We performed a study to evaluate the preventive effects of anisodamine against contrast-induced nephropathy (CIN) in type 2 diabetics with renal insufficiency un...

journal_title：Chinese medical journal

authors： Geng W,Fu XH,Gu XS,Wang YB,Wang XC,Li W,Jiang YF,Hao GZ,Fan WZ,Xue L

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:HATCH score is an established predictor of progression from paroxysmal to persistent atrial fibrillation (AF). The purpose of this study was to determine if HATCH score could predict recurrence after catheter ablation of AF. METHODS:The data of 488 consecutive paroxysmal AF patients who underwent an index c...

journal_title：Chinese medical journal

authors： Tang RB,Dong JZ,Long DY,Yu RH,Ning M,Jiang CX,Sang CH,Liu XH,Ma CS

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:It has been proved that sevoflurane postconditioning (SpostC) could protect the heart against myocardial ischemia/reperfusion injury, however, there has been few research focused on the electrophysiological effects of SpostC. The objective of the study was to investigate the effects of SpostC on action poten...

journal_title：Chinese medical journal

authors： Gong JS,Yao YT,Fang NX,Huang J,Li LH

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:The gradually increasing changes in a human hyperlipidemic diet along with chronic stress might play an important role in the increased numbers of fatty liver. This study investigated the effects of Ilex asprella root decoction on related genes of lipid metabolism in chronic stress in hyperlipidemic fatty li...

journal_title：Chinese medical journal

authors： Hu XY,Shu XC,Guo Y,Ma Y

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Whether antibody to myelin oligodendrocyte glycoprotein (MOG) can be a diagnostic marker for multiple sclerosis (MS) is still controversial. Recent studies suggested that serum specific anti-MOG epitope antibody might be an MS specific marker. However, these studies did not include neuromyelitis optica (NMO)...

journal_title：Chinese medical journal

authors： Xu Y,Zhang Y,Liu CY,Peng B,Wang JM,Zhang XJ,Li HF,Cui LY

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Few clinical studies or randomized clinical trial results have reported the impact of fast track surgery on postoperative insulin sensitivity. This study aimed to investigate the effects of fast track surgery on postoperative insulin sensitivity in patients undergoing elective open colorectal resection. MET...

journal_title：Chinese medical journal

authors： Yang DJ,Zhang S,He WL,Chen HY,Cai SR,Chen CQ,Song XM,Cui J,Ma JP,Zhang CH,He YL

更新日期：2012-09-01 00:00:00

abstract：OBJECTIVE:To review the progress of cardiac differentiation and electrophysiological characteristics of bone marrow mesenchymal stem cells. DATA SOURCES:The databases of PubMed, Springer Link, Science Direct and CNKI were retrieved for papers published from January 2000 to January 2012 with the key words of "bone marr...

journal_title：Chinese medical journal

authors： Liu BW,Lü AL,Hou J,Huang W,Li Y,Hou ZL,Hou H,Da J,Yang N,Ai SY

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:It is the first multicenter clinical study in China to investigate zanamivir use among Chinese adolescents and adults with influenza-like illness (ILI) since 2009, when inhaled zanamivir (RELENZA(®)) was marketed in China. METHODS:An uncontrolled open-label, multicentre study to evaluate the antiviral activ...

journal_title：Chinese medical journal

authors： Cao B,Wang DY,Yu XM,Wei LQ,Pu ZH,Gao Y,Wang J,Dong JP,Li XL,Xu Q,Hu K,Chen BY,Yu YS,Song SF,Shu YL,Wang C

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Chronic liver disease causes aberrant formation of fibrous tissue that impedes normal liver function, ultimately resulting in liver cirrhosis. Iron uptake can occur within the hepatic parenchyma or within the various nodules that form in a cirrhotic liver, termed siderotic nodules (SN). We aimed to investiga...

journal_title：Chinese medical journal

authors： Tao R,You ZL,Zhang JQ,Dai YM,Zhou DQ,Cai P,Fan Y,Cui JG,Wang J

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Volatile anesthetics (VAs) may affect varied and complex physiology processes by manipulating Ca(2+)-calmodulin (CaM). However, the detailed mechanism about the action of VAs on CaM has not been elucidated. This study was undertaken to examine the effects of VAs on the conformational change, hydrophobic site...

journal_title：Chinese medical journal

authors： Zhou MM,Xia HM,Liu J,Xu YN,Xin NX,Zhang SH

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:It has been long suggested that abnormal clinical factors in the body, such as dyslipidemia and diabetes, can affect the presence of atherosclerosis. However, few studies on the effect of factors within the normal range, such as the loss of renal function with age, on the prevalence of atherosclerosis are fe...

journal_title：Chinese medical journal

authors： Jiang SM,Sun XF,Gu HX,Chen YS,Xi CS,Qiao X,Chen XM

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:With features of high tissue contrast, MRI can be used for the qualitative and quantitative evaluation of atherosclerosis plaques. In this study we investigated the development of atherosclerosis plaque with high resolution 3T MRI in a rabbit model and compared the findings with the histopathological results...

journal_title：Chinese medical journal

authors： Ma XH,Zhao L,Zhao QM,Feng TT,Shang JF,Zhang ZQ

更新日期：2012-08-01 00:00:00

abstract：:Pancreatic neuroendocrine tumors (NETs) are one subgroup of gastroenteropancreatic NETs. Its main characteristics are slow growth, frequent metastasis to the liver, and limited to the liver for long periods. In patients with irresectable liver metastatic NET, liver transplantation is the only radical treatment. About ...

journal_title：Chinese medical journal

authors： Chen XB,Yang J,Xu MQ,Yan LN

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:The long-term safety and efficacy of drug-eluting stents (DES) versus bare metal stents (BMS) are unclear and controversial issues in patients with acute ST-elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI). The purpose of this study was to compare the long-t...

journal_title：Chinese medical journal

authors： Wang CH,Fang Q,Zhang SY,Shen ZJ,Fan ZJ,Jin XF,Zeng Y,Liu ZY,Xie HZ,Yang M

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:Copernicus optical coherence tomography (SOCT) is a new, ultra high-speed and high-resolution instrument available for clinical evaluation of optic nerve. The purpose of the study was to compare the agreements between SOCT and Heidelberg retinal tomography (HRT). METHODS:A total of 44 healthy normal volunte...

journal_title：Chinese medical journal

authors： Yang QS,Yu YJ,Li SN,Liu J,Hao YJ

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:Recurrence or metastasis of myxomas is not rare and can lead to malignancy. We aimed to analyze the risk factors for postoperative cardiac myxoma recurrence and to summarize its clinical characteristics, treatments and classification. METHODS:The clinical data of 5 patients with recurrent cardiac myxoma wer...

journal_title：Chinese medical journal

authors： Sheng WB,Luo BE,Liu Y,Zhang H,Zou LJ,Xu ZY,Zhang HY,Ji GY

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:Increasing prevalence of Staphylococcus aureus (S. aureus), particularly methicillin-resistant S. aureus (MRSA) has been reported in China. In this study, we investigated the drug resistance characteristic, genetic background, and molecular epidemiological characteristic of S. aureus in Changsha. METHODS:Be...

journal_title：Chinese medical journal

authors： Zou MX,Zhou RR,Wu WJ,Zhang NJ,Liu WE,Hu FP,Fan XG

更新日期：2012-07-01 00:00:00

abstract：:Atrial fibrillation (AF) is the most common sustained dysrhythmia in clinical practice. The bulk of evidence suggests that inflammatory processes, oxidative stress and matrix metalloproteinase are associated with development of AF. However, these agents may be involved in high mobility group box 1 protein (HMGB1). We ...

journal_title：Chinese medical journal

authors： Hu XR,Wang XH,Liu HF,Zhou WJ,Jiang H

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:In-hospital medical complications are associated with poorer clinical outcomes for stroke patients after disease onset. However, few studies from China have reported the effect of these complications on the mortality of patients with acute ischemic stroke. In this prospective work, the China National Stroke ...

journal_title：Chinese medical journal

authors： Wang PL,Zhao XQ,Yang ZH,Wang AX,Wang CX,Liu LP,Wang YL,Wang XG,Ju Y,Chen SY,Chen QD,Qu H,Lu JJ,Zhang J,Ma RH,Zhang YM,Wang YJ

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) has been successfully used to treat degenerative diseases of the lumbar spine. There are few reports comparing the complications and clinical outcomes in older patients who have undergone one- or two-level MIS-TLIF with those of younger pat...

journal_title：Chinese medical journal

authors： Wu WJ,Liang Y,Zhang XK,Cao P,Zheng T

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Dendritic cells (DCs) are the most important professional antigen presenting cells that play a key role in initiating adaptive immune responses. The depletion and dysfunction of DCs contribute to the development of immunodeficiency or immunoparalysis in some lung diseases. In the present study, we investigat...

journal_title：Chinese medical journal

authors： Wang HW,Lu JY,Wang L,Tian G

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Early onset severe preeclampsia is a specific type of severe preeclampsia, which causes high morbidity and mortality of both mothers and fetus. This study aimed to investigate the clinical definition, features, treatment, outcome and risk factors of early onset severe preeclampsia in Chinese women. METHODS:...

journal_title：Chinese medical journal

authors： Gong YH,Jia J,Lü DH,Dai L,Bai Y,Zhou R

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Tumor necrosis factor-α is a key mediator in the pathogenesis of psoriasis. Infliximab is a monoclonal antibody that specifically binds to tumor necrosis factor-α. The purpose of this study was to validate the efficacy and safety of 5 mg/kg infliximab therapy in Chinese patients with moderate to severe plaqu...

journal_title：Chinese medical journal

authors： Yang HZ,Wang K,Jin HZ,Gao TW,Xiao SX,Xu JH,Wang BX,Zhang FR,Li CY,Liu XM,Tu CX,Ji SZ,Shen Y,Zhu XJ

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Roux-en-Y gastric bypass (GBP) is the main surgical procedure used in type 2 diabetes. The objective of this study was to evaluate the different types of GBP in treatment of type 2 diabetes. METHODS:Patients with type 2 diabetes were randomly divided into two groups: those who underwent gastrojejunal loop a...

journal_title：Chinese medical journal

authors： Pu YD,Li JQ,Cao ZY,Wang L,Hu X,Dong LG,Li YM,Zhao HZ,Qin R,Yang B,He JM,Wu YJ,Wang Y,Lü G,Zhang B,Wang Y,Liu WP,Weng JF

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Chimerism analysis is an important tool for the surveillance of post-transplant engraftment. It offers the possibility of identifying impending graft rejection and recurrence of underlying malignant or non-malignant disease. Here we investigated the quantitative chimerism kinetics of 21 relapsed leukemia pat...

journal_title：Chinese medical journal

authors： Qin XY,Li GX,Qin YZ,Wang Y,Wang FR,Liu DH,Xu LP,Chen H,Han W,Wang JZ,Zhang XH,Li JL,Li LD,Liu KY,Huang XJ

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Acute lung injury (ALI) and end-stage acute respiratory distress syndrome (ARDS) were among the most common causes of death in intensive care units. The activation of an inflammatory response and the damage of pulmonary epithelium and endotheliumwerethe hallmark of ALI/ARDS. Recent studies had demonstrated t...

journal_title：Chinese medical journal

authors： Xu YL,Liu YL,Wang Q,Li G,Lü XD,Kong B

更新日期：2012-06-01 00:00:00